FAQs: After Approval

What do I do if my protocol expires?

If your protocol expires, all work with vertebrate animals must stop immediately. You are not allowed to conduct research on animals until the protocol is approved. Federal funds cannot be used to pay per diems or animal support costs during the period of expiration.

However, laboratory personnel are responsible for working with their LARC manager to ensure that animals on study receive appropriate care while the protocol is expired. This may include:

  • PI feeding or watering animals (e.g. antibiotic feed or water, special diets)
  • Medications, including antibiotics and analgesics
  • Visually observing animals for pain, distress, or ill health (e.g. seizures)
  • Measurements needed to evaluate health status (e.g. blood glucose, measuring tumor size)
  • Maintenance of implants or other medical devices

Breeding animals do not need to be separated, and lab staff should continue to wean litters; however, new breeding pairs are not allowed